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Author: Admin | 2025-04-28
(Imitrex)certain opioid pain medications, such as tramadol (Conzip, Ultram) or fentanyl (Duragesic, Subsys, Actiq, others)certain antipsychotics, such as quetiapine (Seroquel)amphetamine or stimulant drugs, such as amphetamine/dextroamphetamine (Adderall, Mydayis), methylphenidate (Ritalin), or lisdexamfetamine (Vyvanse)buspirone (Buspar), a drug for anxietylithium (Lithobid), a drug for bipolar disorder and depressionBlood thinners. Blood thinners are drugs used to treat and help prevent blood clots. Taking Lexapro with blood thinners can raise your risk of bleeding.* Examples of blood thinners include: apixaban (Eliquis)dabigatran (Pradaxa)rivaroxaban (Xarelto)warfarin (Jantoven)Nonsteroidal anti-inflammatory drugs (NSAIDs).NSAIDs are drugs that reduce inflammation and relieve pain. Taking Lexapro with NSAIDs can increase your risk of bleeding.* Examples of NSAIDs include: aspirindiclofenac (Zorvolex, Zipsor)ibuprofen (Advil, Ibu-tab, Motrin)naproxen (Aleve, Naprosyn)Diuretics.Diuretics are drugs used to treat fluid retention, high blood pressure, and heart failure. Taking Lexapro with diuretics can raise your risk of hyponatremia (low level of sodium in your blood).* Examples of diuretic drugs include: furosemide (Lasix)hydrochlorothiazideCYP2D6 substrates. These are drugs that are broken down by an enzyme (a type of protein) in your liver called CYP2D6. Lexapro may decrease the activity of CYP2D6. So taking Lexapro with these drugs could make them build up in your body. This could increase your risk of side effects from CYP2D6 substrates. Examples include: aripiprazole (Abilify)desipramine (Norpramin)dextromethorphanflecainidemetoprolol (Lopressor, Toprol XL, others)propafenone (Rythmol SR)Gabapentin (Neurontin). Gabapentin is a drug used for seizures and certain types of nerve pain. Taking Lexapro with gabapentin could increase your risk of side effects from both drugs. It could also make gabapentin less effective at treating seizures.* For more details about this side effect, see the “Lexapro side effects” section above. † Your doctor typically won’t prescribe Lexapro if you’ve taken an MAOI antidepressant in the last 14 days. And they typically won’t prescribe an MAOI antidepressant until at least 14 days after you’ve stopped taking Lexapro.Lexapro and herbs and supplementsTaking certain herbs and supplements with Lexapro can increase your risk of serotonin syndrome. Due to this risk, your doctor will likely recommend you don’t take these herbs and supplements with Lexapro. Examples include:St. John’s wort (also called Hypericum perforatum)tryptophan5-hydroxytryptophanIf you’re interested in taking other herbs
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