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Author: Admin | 2025-04-28
The effective substance) ranges from 18 to 50 hours. Generally, it takes about five half-lives for a medicine to be out of your system. So, some of your Klonopin doses may remain in your body for up to 10 days. Be aware that long-term use of Klonopin may cause physical dependence (when you need a medicine to function) or tolerance (when your body gets used to a medicine and a higher dose is needed to get the same benefit). How Does Klonopin Compare to Other Medications? Many medications may be prescribed for anxiety or panic disorders. Here are some distinctions between Klonopin and other anxiety medications. Klonopin vs. Other Benzodiazepines There is some variability in BZD onset time—how soon medicines start to work. Klonopin starts to work later than many common BZDs, including Xanax (alprazolam) and Valium (diazepam). Valium starts working within 30 minutes, while Xanax starts working in 15 minutes to an hour. There are also differences in how long BZD medicines work in the body. Klonopin falls between Xanax and Valium in this category. Xanax is short-acting, with a half-life of six to 27 hours, while Valium is long-acting, with a half-life of 20 to 80 hours. Onset time and duration of effect often dictate where one medication may be preferred to another for specific patient scenarios. For instance, long-acting BZDs like Klonopin are less risky in terms of overdose (taking too much medication), so they would be preferable for people with a history of substance abuse. In this vein, Klonopin can be used to help manage withdrawal from shorter-acting BZDs. Valium is approved not only for seizures and anxiety disorders but also for alcohol withdrawal and muscle spasms. Klonopin vs. Non-Benzodiazepine Alternatives Other medications that are commonly prescribed for anxiety include the following:Selective serotonin reuptake inhibitors (SSRIs) like Prozac (fluoxetine) and Zoloft (sertraline)Serotonin-norepinephrine reuptake inhibitors (SNRIs) like Cymbalta (duloxetine) and Effexor (venlafaxine)Antihistamines like Vistaril (hydroxyzine) and Buspar (buspirone) These medicines take longer to work than BZDs. For instance, Buspar can take up to four weeks to work, and SSRIs or SNRIs may take two months. Despite this,
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