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Author: Admin | 2025-04-28
Sold under the brand name Wellbutrin®, bupropion is a medication that’s commonly prescribed in the treatment of depression. Sold under the brand name Wellbutrin XL®, it’s also used to treat seasonal affective disorder (SAD) and, when sold as Zyban®, as a medication to help people quit smoking.Although bupropion is less likely to cause certain side effects than other antidepressants, there are still numerous side effects that you should be aware of if you currently use bupropion or are considering this medication. Below, we’ve listed the side effects you may experience while using bupropion, with information on how frequently each side effect occurs, what you can do to manage it and your best options if any particular side effect persists. Bupropion is an antidepressant medication used to help treat the symptoms of depression. Its most common side effects are similar to those of many other medications prescribed to treat depression. As with other antidepressants, most side effects that are associated with bupropion occur in the first few weeks of treatment and go away over time.Common side effects of bupropion include:AgitationDry mouthInsomniaHeadache or migraineNausea and vomitingConstipationTremorDizzinessExcessive sweatingBlurred visionTachycardiaConfusionRashHostilityCardiac arrhythmia (irregular heartbeat)Weight lossAuditory disturbanceOf these, the most common side effects reported in clinical trials of bupropion were constipation, dizziness, dry mouth, headaches/migraines, nausea/vomiting, excessive sweating, agitation and tremor, which were all reported by more than 20 percent of users.AgitationAgitation was the most common side effect reported in clinical trials of Wellbutrin, a medication containing bupropion prescribed to treat major depressive disorder (MDD) and seasonal affective disorder. According to data from the FDA, 31.9 percent of people reported agitation while using bupropion.Other side effects associated with agitation include insomnia, which affected about 18 percent of bupropion users in clinical trials.If you feel agitated after using bupropion and don’t notice this side effect improving in the first few weeks of treatment, talk to your healthcare provider. They may adjust your bupropion dosage or recommend other changes to manage this side effect.Try to exercise regularly. Other techniques that may help include deep-breathing exercises and yoga. If you continue to feel agitated while using bupropion, you may also want to talk to your healthcare provider about using medication to help you relax or switching to a different antidepressant.If you find it difficult to sleep after taking bupropion, avoid taking your medication close to your bedtime. Using bupropion earlier in the day will mean that a lower dose of the medication will be in your bloodstream at bedtime, which may make it easier for you to fall asleep. And vice versa, if you find yourself saying, “Boy, Wellbutrin makes me tired” it may be worth talking to your healthcare provider about taking it at night, closer to bedtime.Dry MouthBupropion and other antidepressants may cause xerostomia, or dry mouth. This side effect was reported by 27.6 percent of people who were prescribed bupropion in clinical trials, making it the second-most common side effect after agitation.Dry mouth is a common side effect of many antidepressants, not only bupropion. It may
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