IV, intravenous; PO, oral; SR, sinus rhythm. Eur Heart J. 2024 Oct;15 PO amiodarone 25.7 mg/kg vs. IV amiodarone 3-5 mg/kg bolus
IV to PO conversion of Amiodarone after 48 hours. Special Instructions: If the patient is taking other PO meds then stop the infusion and order 400 mg PO bid.
Amiodarone IV Dosing Amiodarone PO dosing in hospital. After converts to NSR or after 24 hrs, 400mg PO BID up to 10g load (includes IV), then 200mg daily.
PO AMIODARONE: COMPARING RISKS. Amiodarone Cardiac Toxicities. Bradycardia. Heart Block ?Hypotension. Acute. Bradycardia. Heart block. QTc
PO amiodarone 25.7 mg/kg vs. IV amiodarone 3-5 mg/kg bolus then mg/kg over 24 h. No difference in conversion to SR between PO and IV.
IV to PO conversion of Amiodarone after 48 hours. Special Instructions: If the patient is taking other PO meds then stop the infusion and order 400 mg PO bid.
Conversion from IV to oral (PO) amiodarone will occur based on patient 50% bioavailability of PO versus IV amiodarone). The primary
3. Amiodarone pharmacology. Loading with amiodarone can be done in several ways IV, PO, IV followed by PO, or IV and PO together. The loading regimen employed depends on the clinical indication and the rapidity of effect desired. More rapid loading slightly increases the risk of acute side effects.
IV amiodarone. ▫ ≤ 24hours on IV amiodarone: start mg po Q12h. ▫ ≥ 48hours on IV amiodarone: start 200mg po q12h. ▫ Decrease the dose by half once
Comments
Boyd