In addition, taking into consideration the ratio between the trazodone and gabapentin ED 50 values (1.2:27.8), the fixed drug-dose ratio, based on mass quantity for trazodone and gabapentin, was established at 1:23.2.
Trazodone may be helpful in men with ED, possibly more so at higher doses, and in men with psychogenic ED. Future high-quality trials should compare trazodone with placebo
Trazodone may be helpful in men with ED, possibly more so at higher doses, and in men with psychogenic ED. Future high-quality trials should compare trazodone with placebo and other therapies in men with depression and psychogenic ED. KEYWORDS erectile dysfunction, trazodone, impotence, meta-analysis, treatment outcome, adverse events
Panel D: Isobologram for the combination of trazodone and gabapentin in the writhing test in mice. The ED 50 values are individually plotted for each drug on the axes and the straight line connecting trazodone and gabapentin ED 50 values is the theoretical additive line.
In addition, taking into consideration the ratio between the trazodone and gabapentin ED 50 values (1.2:27.8), the fixed drug-dose ratio, based on mass quantity for trazodone and gabapentin, was established at 1:23.2.
Panel D: Isobologram for the combination of trazodone and gabapentin in the writhing test in mice. The ED 50 values are individually plotted for each drug on the axes and the straight line connecting trazodone and gabapentin ED 50 values is the theoretical additive line.
Trazodone may be helpful in men with ED, possibly more so at higher doses, and in men with psychogenic ED.
Panel D: Isobologram for the combination of trazodone and gabapentin in the writhing test in mice. The ED 50 values are individually plotted for each drug on the axes and the straight line connecting trazodone and gabapentin ED 50 values is the theoretical additive line.
In addition, taking into consideration the ratio between the trazodone and gabapentin ED 50 values (1.2:27.8), the fixed drug-dose ratio, based on mass quantity for trazodone and gabapentin, was established at 1:23.2.
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