Ivosidenib package insert

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Actual: The product package insert recommends considering other therapies that are not strong CYP3A4 inhibitors while patients receive glasdegib . If strong CYP3A4 inhibitors cannot be avoided, Ivosidenib (Tibsovo ) Ivosidenib is an IDH1 inhibitor that was FDA approved in
4.6 rating 2025-04-24
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On day 31 of ivosidenib, her platelet count was 189 10 3 /mcL, and on day 34, a bone marrow biopsy confirmed a complete remission (CR) Ivosidenib [package insert]. Cambridge, MA: Agios Pharmaceuticals, Inc; 2025. [Google Scholar] Other Formats. PDF (838K) Actions. Cite; Collections. Add to Collections.

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There are currently no contraindications for ivosidenib included in the package insert. Current warnings and precautions for ivosidenib in cholangiocarcinoma include the following: Of the 123 patients with cholangiocarcinoma on ivosidenib in the ClarIDHy study, 2 percent were found to have QTc 500 msec and 5 percent had an increase from

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Tibsovo (ivosidenib) has been approved for previously treated, locally advanced or metastatic cholangiocarcinoma with an IDH1 mutation. Tibsovo [package insert]. Boston, MA: Servier

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Ivosidenib and azacitidine in IDH1-mutated acute myeloid leukemia. N Engl J Med. 2024;386(16): . doi:10.1056/NEJMoa 2. Tibsovo. Package insert.

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Product Package Inserts. 1. Somatuline Depot [package insert]. Basking Ridge Eligard [package insert]. Fort Collins, CO: Tolmar Pharmaceuticals, Inc

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Ivosidenib (Tibsovo) package insert; Ivosidenib (Tibsovo) patient drug information (Chemocare) History of changes in FDA indication Acute myeloid leukemia. : Granted approval for adult patients with relapsed or refractory acute myeloid leukemia (AML) with a susceptible IDH1 mutation as detected by an FDA-approved test.

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Coadministration of strong CYP3A4 inhibitors such as posaconazole and voriconazole should be avoided; if using these agents is unavoidable, the dose of ivosidenib should be decreased to 250 mg daily per the package insert (Agios Pharmaceuticals, Inc, 2025). A population pharmacokinetic evaluation found that the use of moderate/strong CYP3A4

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Glofitamab [package insert]. Genetech US, Inc. Epcoritamab [package insert]. Genmab US, Inc.LUNSUMIO [package insert]. Genentech, Inc. Page

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GSK's Arexvy package insert Pfizer's Abrysvo package insert Moderna's mResvia package insert. To learn more, see ACIP Contraindications

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