Elderly: The elderly has an increased frequency of adverse reactions to NSAIDs especially gastrointestinal bleeding and perforation which may be
Morphine is substantially excreted by the kidney; risk of adverse reactions may be greater in patients with impaired renal function, and elderly patients are more likely to have decreased renal function. Hepatic Impairment. Morphine pharmacokinetics are significantly altered in patients with cirrhosis.
Elderly patients, in whom there is reduced If the patient has been using an analgesic other than morphine, estimate the morphine
Morphine is substantially excreted by the kidney; risk of adverse reactions may be greater in patients with impaired renal function, and elderly patients are more likely to have decreased renal function.
Selected adverse drug reactions/Precautions unique to morphine: Active Elderly, cachectic, or debilitated patients: use with extreme caution due to
elderly or debilitated and those with severe The adverse reactions caused by morphine are essentially those observed with other opioid analgesics.
Do not use Morphine Sulfate Injection while you are breastfeeding as morphine Use in the elderly: Morphine doses need to be reduced in elderly patients.
by O Linares 2024a decrease in first-pass hepatic metabolism of morphine in the elderly. Our results suggest that reduced morphine CL in the elderly is due, in part, to an age
Fig. 1 Adverse skin reaction in an elderly patient: urticaria due to amitriptyline. - Drug eruptions in the elderly.
Regards, Jack