This topic discusses risk factors for warfarin-associated bleeding and poor international normalized ratio (INR) control and presents an approach to the management of a patient with warfarin-associated bleeding or an INR above the therapeutic range (ie, a supratherapeutic INR).
infection at the time of supratherapeutic INR and concurrent medications) were presented in frequency and percentage. For the comparison between the two outcome groups (Supratherapeutic INR versus Non Supratherapeutic INR), Chi-square test was used for categorical variables, while t-test was used for continuous variables.
For patients initiating prednisone therapy, preemptive warfarin dose reduction resulted in a non-significant reduction in supratherapeutic INR but increased the likelihood of subtherapeutic INR compared to INR monitoring with reactive warfarin dose adjustment.
For patients initiating prednisone therapy, preemptive warfarin dose reduction resulted in a non-significant reduction in supratherapeutic INR but increased the likelihood of subtherapeutic INR compared to INR monitoring with reactive warfarin dose adjustment.
defined by age over 65 (E), and drugs associated with bleeding (e.g. Supratherapeutic INR but INR 4.5, no bleeding. Lowering the dose or omit a
Individual patient circumstances may mean that practice diverges from this LOP. Search for the reason(s) for supratherapeutic INR. INR greater
For patients initiating prednisone therapy, preemptive warfarin dose reduction resulted in a non-significant reduction in supratherapeutic INR but increased
General principles for preventing supratherapeutic INR involve careful monitoring and consideration of warfarin-drug interactions, including avoiding
by I Safatly Cited by 2therapy presenting to the ED with a supratherapeutic INR with or without bleeding, stipulating the treatment Continuous data were reported using mean (
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