Methotrexate has many interactions. Some people need to take both an NSAID like meloxicam and methotrexate to control joint inflammation. But you should know that they can interact. Meloxicam can affect how quickly your kidneys clear methotrexate from the body. This can raise your risk of developing methotrexate toxicity (high methotrexate
Methotrexate: A study in 13 rheumatoid arthritis (RA) patients evaluated the effects of multiple doses of meloxicam on the pharmacokinetics of methotrexate taken once weekly. Meloxicam did not have a significant effect on the pharmacokinetics of single doses of methotrexate.
When meloxicam is used in combination with methotrexate (Rheumatrex, Trexall) or aminoglycosides (for example, gentamicin) the blood levels of the methotrexate
As nouns the difference between methotrexate and meloxicam is that methotrexate is (medicine) an antimetabolite and antifolate drug used in treatment of
Methotrexate: A study in 13 rheumatoid arthritis (RA) patients evaluated the effects of multiple doses of meloxicam on the pharmacokinetics of methotrexate taken once weekly. Meloxicam did not have a significant effect on the pharmacokinetics of single doses of methotrexate.
Methotrexate. Meloxicam did not have a significant effect on the pharmacokinetics of single doses of methotrexate. In vitro, methotrexate did not displace meloxicam from human serum binding sites. However, as with other NSAIDs, meloxicam may increase the haematologic toxicity of methotrexate.
Applies to: methotrexate and meloxicam Meloxicam may increase the blood levels and side effects of methotrexate. You may be more likely to experience this interaction if you have kidney disease or are receiving a high dose of methotrexate.
meloxicam. Meloxicam-DP, PICMI Methadone hydrochloride. Methoblastin, CMIPI, Methotrexate. Methoblastin Blister, CMIPI, methotrexate sodium. Methotrexate
plasma concentration of methotrexate possibly increased by levetiracetam. Meloxicam excretion of methotrexate reduced by meloxicam (increased risk of toxicity).
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