Drugs cause hyponatremia

1 In up 14% of patients with hyponatremia, the problem may be drug-induced,1,2 with thiazide diuretics being the most common cause of drug-induced hyponatremia.

Carbamazepine often causes drug-induced hyponatremia. Hyponatremia due to carbamazepine may be improved by changing to the same mechanism of

Studies indicate that 30% of hyponatremia cases are drug-induced [1]. additional drugs that have been known to cause hyponatremia were excluded

drugs that increase ADH secretion, among other causes. Cancer accounts cause of their hyponatremia. However, not every person with hyponatremia and

drugs are commonly implicated in drug-induced hyponatremia. lead to SIADH, which causes hypotonic hyponatremia in a euvolemic patient.

Hyponatremia-related to drug treatment can be caused by dozens, perhaps hundreds, of medications. Table 6.1 lists the drugs associated with hyponatremia. Table 6.1 Causes of drug-induced hyponatremia according to probable underlying mechanisms

This review in AJKD lists most of the causes of drug-induced hyponatremia and provides the rationale for why hyponatremia occurs in the setting of these drugs.

Certain drugs commonly used in patients with cancer are known to cause hyponatremia by inducing SIADH Cisplatin may also cause hyponatremia by damaging

However, many drugs were not included in the investigators' list of medications that cause hyponatremia. Nicotine patch therapy can induce hyponatremia. The