It is estimated that 1.3 mg of intramuscular (IM) hydromorphone is equianalgesic to 10 mg of IM morphine. The relative potency, (based on a single dose bioassay) of oral hydromorphone was found to be approximately one-fifth that of IM hydromorphone, this ratio being similar to that for morphine.
Intramuscular Morphine Sulfate. 5mg to 10mg intramuscular (IM). It will take minutes for IM Morphine to have a peak effect. Dose may be repeated once
Chemically, morphine sulfate is 7,8-didehydro-4,5α-epoxy-17 morphine IM for every 6 mg of morphine as MS CONTIN. The IM 24-hour dose
It is estimated that 1.3 mg of intramuscular (IM) hydromorphone is equianalgesic to 10 mg of IM morphine. The relative potency, (based on a single dose bioassay) of oral hydromorphone was found to be approximately one-fifth that of IM hydromorphone, this ratio being similar to that for morphine.
all incremental morphine doses must be no greater than 2.5 mg IV or 5 mg IM. Morphine (preference for single IM dose) is a suitable analgesic for the.
Oral morphine. . . . . IM/IV morphine (based on a 1:3 IM/IV:PO ratio). . . .
IN BOTH CASES, HOWEVER, THE AIM IS TO ESTIMATE THE NEW DOSE CONSERVATIVELY. For example, to estimate the required 24-hour dose of morphine for IM use, one could employ a conversion of 1 mg of morphine IM for every 6 mg of morphine as MS CONTIN. The IM 24-hour dose would have to be divided by six and administered on a q4h regimen.
Intramuscular Morphine Sulfate. 5mg to 10mg intramuscular (IM). It will take minutes for IM Morphine to have a peak effect. Dose may be repeated once
IV doses are typically 25 to 50 mg and IM doses are 50 to 100 mg. It has a faster onset of action-five to 10 minutes for IV dosing and 45 minutes for IM dosing-than morphine does. As with morphine, meperidine can cause neonatal respiratory depression.
Comments
Regards, Jack